https://ogma.newcastle.edu.au/vital/access/ /manager/Index en-au 5 https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:45126 Wed 26 Oct 2022 12:58:45 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:43508 Wed 21 Sep 2022 10:29:35 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:14230 dp for a free falling penetrometer, and to find the relation between this factor and the geotechnical properties of a layer of cohesive soil. It is demonstrated that the dynamic soil resistance can be obtained as the product of its undrained shear strength and the dynamic cone penetration factor, and the latter depends on several parameters such as the rigidity index of the soil, the rate of loading and the rate of shear strength increase with depth of the soil. A wide range of numerical predictions is discussed here and a closed-form expression is derived for the dynamic penetration factor. Comparisons are also made between the deduced values of N_dp and published values of the conventional cone factor, N_c.]]> Wed 11 Apr 2018 10:48:00 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24419 Wed 10 Nov 2021 15:05:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21463 Tue 24 Aug 2021 14:29:37 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:54213 Tue 13 Feb 2024 11:50:24 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:44255 p < 0.05) between the two particle size fractions of < 2 mm and < 250 μm; (2) EC, CEC and total Pb were significantly correlated to Pb bioaccessibility (p < 0.05); and (3) soil analyses based on source of Pb demonstrated a strongly significant relationship between Pb bioaccessibility and soil properties (CEC, EC, clay content and total Pb) for mining soils from Broken Hill (r² = 0.86, p < 0.05, n = 18). These results demonstrated the influences of Pb contamination sources, soil properties and particle size fractions on Pb bioaccessibility as well as the prediction of Pb bioaccessibility using soil properties. The findings documented here will help in developing a predictive tool for human health risk assessment and the remediation of Pb contaminated soils.]]> Tue 11 Oct 2022 12:44:05 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:32391 Thu 28 Oct 2021 12:36:12 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:55007 Thu 28 Mar 2024 13:58:38 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46441 Thu 24 Nov 2022 14:07:36 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:34677 In vivo studies were conducted using juvenile swine as a surrogate model for young children. Two compartment pharmacokinetic models were used to analyze the biological response produced by Pb oral solution and spiked soils. Absolute and relative bioavailability of Pb in soils (oral dose of 100 µ g Pb/kg body weight/day) were estimated by comparing them with intravenously administered soluble Pb salt (25 µ g Pb/kg/day) and orally administered the same Pb salt [Pb acetate = (CH₃COO)₂Pb·3H₂O] administered to 3 juvenile pigs per treatment. Lead bioaccessibility was calculated using the in vitro RBALP (i.e. relative bioaccessibility leaching procedure) method. The in vitro results of RBALP were compared to in vivo relative Pb bioavailability to ascertain whether the changes in bioaccessibility correlated with the in vivo data. Although the in vivo Pb relative bioavailability (RB) in all soils except in MLA (Mount Lofty Acidic) revealed an increase (18%-159%) in the presence of Zn, the in vitro RBALP bioaccessibility results indicated otherwise (1%-38% decrease). In vivo RB of Pb in MLA declined by 37% in the presence of Zn. However, the RBALP in vitro bioaccessible Pb did not correlate with the relative bioavailabilities of Pb in the juvenile swine dosing experiment. Caution is therefore needed when predicting Pb bioavailability/bioaccessibility in the presence of metal mixtures. The literature contains much information on the correlation of metal and metalloid bioaccessibility with their bioavailability. There is, however, a paucity of studies investigating the effects of other metals on Pb and their IVIVC (in vitro and in vivo correlations). The current study addresses this knowledge gap by assessing in vivo and in vitro bioavailability of Pb in the presence of Zn.]]> Thu 11 Apr 2019 15:08:08 AEST ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30285 Thu 09 Dec 2021 11:02:06 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:12118 Sat 24 Mar 2018 08:11:03 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17436 Sat 24 Mar 2018 08:01:35 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21064 Sat 24 Mar 2018 07:59:26 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:21558 Sat 24 Mar 2018 07:49:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27997 Sat 24 Mar 2018 07:38:41 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:26348 Sat 24 Mar 2018 07:35:54 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:31024 Sat 24 Mar 2018 07:34:51 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30284 Sat 24 Mar 2018 07:33:35 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:27553 Sat 24 Mar 2018 07:33:15 AEDT ]]> https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35882 Fri 10 Jan 2020 10:06:23 AEDT ]]>